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tubb4a protein  (Human Protein Atlas)

 
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    Structured Review

    Human Protein Atlas tubb4a protein
    The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
    Tubb4a Protein, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/tubb4a protein/product/Human Protein Atlas
    Average 90 stars, based on 1 article reviews
    tubb4a protein - by Bioz Stars, 2026-06
    90/100 stars

    Images

    1) Product Images from "Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma"

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    Journal: Current Protein & Peptide Science

    doi: 10.2174/1389201023666220928120902

    The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
    Figure Legend Snippet: The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

    Techniques Used:

    Univariate and Multivariate Cox analysis of 13 candidate genes.
    Figure Legend Snippet: Univariate and Multivariate Cox analysis of 13 candidate genes.

    Techniques Used:

    Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).
    Figure Legend Snippet: Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

    Techniques Used: Expressing, Significance Assay

    Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).
    Figure Legend Snippet: Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

    Techniques Used: Immunohistochemistry, Quantitative RT-PCR, Expressing

    Prediction of miRNAs binding to TUBB4A.
    Figure Legend Snippet: Prediction of miRNAs binding to TUBB4A.

    Techniques Used: Binding Assay

    Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).
    Figure Legend Snippet: Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

    Techniques Used: Expressing

    The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).
    Figure Legend Snippet: The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

    Techniques Used: Expressing, Significance Assay

    The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).
    Figure Legend Snippet: The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

    Techniques Used:

    The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.
    Figure Legend Snippet: The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.

    Techniques Used:

    Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.
    Figure Legend Snippet: Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

    Techniques Used: Expressing

    Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).
    Figure Legend Snippet: Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

    Techniques Used:

    Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).
    Figure Legend Snippet: Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

    Techniques Used: Diagnostic Assay, Expressing



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    tubb4a protein  (Human Protein Atlas)
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    Human Protein Atlas tubb4a protein
    The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.
    Tubb4a Protein, supplied by Human Protein Atlas, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Image Search Results


    The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: The common upregulated/downregulated differentially expressed genes(DEGs) identified among GSE15605, GSE3189.

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques:

    Univariate and Multivariate Cox analysis of 13 candidate genes.

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Univariate and Multivariate Cox analysis of 13 candidate genes.

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques:

    Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Expression levels of DLL3 and TUBB4A ( A,B ),“*” represents “p-value < 0.05”;Disease Free Survival(DFS) ( C,D ); Progress Free Interval (PFI) ( E,F ); Disease Specific Survival (DSS) ( G,H ).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Expressing, Significance Assay

    Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Immunohistochemistry images of TUBB4A in SKCM tissues and normal skin tissues from Human Protein Atlas ( A ). The results of RT-qPCR of TUBB4A expression levels in skin cutaneous melanoma cell lines ( B ). ***, **, and * represent significant differences between skin cutaneous melanoma cell lines and human primary normal skin melanocytes, respectively (P<0.001, P<0.01, P<0.05).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Immunohistochemistry, Quantitative RT-PCR, Expressing

    Prediction of miRNAs binding to TUBB4A.

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Prediction of miRNAs binding to TUBB4A.

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Binding Assay

    Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Upstream potential miRNAs predicted to bind to TUBB4A. The miRNA-TUBB4A network ( A ). Overall survival (OS) of miRNAs in TCGA-SKCM cohort ( B ). The expression of TUBB4A and hsa-let-7b-5p in SKCM was negatively correlated ( C ). The expression of TUBB4A and hsa-miR-423-5p in SKCM was positively correlated ( D ).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Expressing

    The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: The upstream lncRNAs of hsa-let-7b-5p in SKCM. The lncRNAs-hsa-let-7b-5p network ( A ). The expression levels of SNHG16 in skin cutaneous melanoma compared with TCGA normal and GTEx data controls ( B ), “*” represents “p-value < 0.05”. The expression of hsa-let-7b-5p and SNHG16 in SKCM was negatively correlated ( C ). The expression of TUBB4A and SNHG16 in SKCM was positively correlated ( D ).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Expressing, Significance Assay

    The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: The co-expressed genes of TUBB4A in SKCM through UALCAN and GEPIA database ( A ). The top 8 enriched in biological process (BP), cellular component (CC), molecular function (MF)items for the co-expressed genes of TUBB4A ( B ). The top 8 enriched in KEGG for the co-expressed genes of TUBB4A ( C ).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques:

    The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: The co-expressed genes of TUBB4A commonly appeared in UALCAN database and GEPIA database.

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques:

    Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Correlation analysis. The expression of TUBB4A in SKCM was positively correlated with the expression of T cell CD4+ Th1 and T cell NK, respectively, by XCELL immune infiltration analysis.

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Expressing

    Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Associations with Clinicopathologic Characteristics in SKCM Patients Using Cox Regression. C-index: 0.725(0.699-0.750).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques:

    Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

    Journal: Current Protein & Peptide Science

    Article Title: Dysregulation of SNHG16(lncRNA)-Hsa-Let-7b-5p(miRNA)-TUBB4A (mRNA) Pathway Fuels Progression of Skin Cutaneous Melanoma

    doi: 10.2174/1389201023666220928120902

    Figure Lengend Snippet: Diagnostic Value of TUBB4A Expression in SKCM. Forest plot of the multivariate Cox regression analysis in SKCM ( A ). A receiver operating characteristic (ROC) curve in SKCM between tumor and normal samples ( B ). A nomogram for predicting the probability of patients with 1-, 3- and 5-year overall survival (OS) ( C ). Calibration curve of the nomogram in 1-year,3-year and 5-year ( D-F ).

    Article Snippet: TUBB4A protein was not expressed in normal skin tissue but had low and moderate expression in skin melanoma tissue from the Human Protein Atlas database.

    Techniques: Diagnostic Assay, Expressing